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Mpex Initiates A Phase 2 Clinical Trial Of Aerosol MP-376 In The Treatment Of Chronic Bacterial Infections In Cystic Fibrosis Patients




Mpex Pharmaceuticals, Inc. announced that it has initiated a Phase 2 clinical study with MP-376 for the treatment of pulmonary infections due to Pseudomonas aeruginosa and other bacteria in patients with cystic fibrosis. MP-376 is Mpex's proprietary aerosol formulation of levofloxacin, an antibiotic that has potent activity against key bacterial pathogens, including Pseudomonas aeruginosa.


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Listen to The Lancet: 21 June
Drug-eluting stents revolutionised interventional cardiology owing to their pronounced ability to reduce restenosis compared with bare-metal stents. Attention has now shifted to safety of these devices because of evidence suggesting an association with late stent thrombosis. In a review, Anthony Bavry and Deepak Bhatt assess current evidence from randomised trials, and propose guidelines for the appropriate use of drug-eluting stents in clinical practice. Deepak Bhatt discusses the history of stents and assesses our current knowledge and considers treatment options for cardiologists and patients in this week's podcast.
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ASCB Statement on Senate Passage of H.R. 810, the Stem Cell Research Enhancement Act
For the second time in as many years, our nation's lawmakers are about to debate the expansion of the federal government's policy regarding the funding of human embryonic stem cell research.
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ZOOM SB246 STREETBOXX RHYTHM MACHINE - HIP HOP NEW
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End Date: Monday Aug-04-2008 2:18:20 BST
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Medtech Startups, December 2007
New medical technologies represented in companies added (December 2007) to the Medtech Startups Database and/or added to the December 2007 issue of MedMarkets.

The following are brief technology descriptions for companies newly added to the MedMarket Diligence Medtech Startups Database and/or covered in MedMarkets Startups during the month of December:

  • EEG analysis for applications such as detection and prediction of seizure.
  • Drugs targeting inflammatory and metabolic pathways, including obesity, type 2 diabetes and cardiovascular disease.
  • In vivo transdifferentiation to regenerate ischemic or diseased organs.
  • Developing small molecule drugs to reprogram adult stem cells.
  • Orthopedic devices for pediatric and other small stature patients.
  • Devices and apparatus for insertion of flexible implants (e.g. breast implants, others).
  • Implantable devices; e.g., to prevent cerebrospinal fluid leaks.
  • Minimally invasive spinal instrumentation.
  • Intra-operative 3D imaging for earlier diagnosis of breast cancer.

Now Published!: Worldwide Wound Management 2007-2016. see link

For coverage in specific issues of MedMarkets, see link.

For details on the Medtech Startups Database, see link.

Tags: medtech, startup
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Obesity not a contraindication to knee replacement (Reuters)
Reuters - Obese individuals with arthritic knees should not be denied knee replacement surgery, researchers conclude, based on a new study showing that obese patients benefit from the surgery almost as much as their normal-weight peers.
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[Biochemistry] The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae

The origin recognition complex (ORC) is conserved in all eukaryotes. The six proteins of the Saccharomyces cerevisiae ORC that form...

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Cystic Fibrosis News From Medical News Today
By editors@medicalnewstoday.com (MNT Editors) - Copyright 2008 Medical News Today - version: v1.5 build A